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Article

Virus-Induced Silencing of Key Genes Leads to Differential Impact on Withanolide Biosynthesis in the Medicinal Plant, Withania somnifera.

Plant & cell physiology - 1 Feb 2018

Agarwal Aditya Vikram, Singh Deeksha, Dhar Yogeshwar Vikram, Michael Rahul, Gupta Parul, Chandra Deepak, Trivedi Prabodh Kumar

Abstract excerpt

Withanolides are a collection of naturally occurring, pharmacologically active, secondary metabolites synthesized in the medicinally important plant, Withania somnifera. These bioactive molecules are C28-steroidal lactone triterpenoids and their synthesis is proposed to take place via the mevalonate (MVA) and 2-C-methyl-d-erythritol-4-phosphate (MEP) pathways through the sterol pathway using 24-methylene...

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PMID: 29165715
DOI: 10.1093/pcp/pcx179

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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