Article
Association Between LTF Polymorphism and Risk of HIV-1 Transmission Among Zambian Seropositive Mothers.
Current HIV research - 1 Jan 2018
Zupin Luisa, Polesello Vania, Segat Ludovica, Kamada Anselmo Jiro, Kuhn Louise, Crovella Sergio
Abstract excerpt
BACKGROUND: Lactoferrin is a member of the innate immune system acting in the first line of defence against pathogens, and it is known for its antibacterial, antifungal and antiviral activity, including HIV-1. Two polymorphisms, T29A and R47K, in the exon 1 region of the LTF gene (encoding for the lactoferrin protein) were previously described as able to influence the lactoferrin antimicrobial function....
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