Article
Suicidal ideation in systemic lupus erythematosus: NR2A gene polymorphism, clinical and psychosocial factors.
Lupus - 1 Apr 2018
Buji R I, Abdul Murad N A, Chan L F, Maniam T, Mohd Shahrir M S, Rozita M, Shamsul A S, Mohamad Hussain R, Abdullah N, Jamal R, Nik Jaafar N R
Abstract excerpt
Background Systemic lupus erythematosus (SLE) patients are a high-risk population for suicide. Glutamatergic neurosystem genes have been implicated in the neurobiology of depression in SLE and suicidal behaviour in general. However, the role of glutamate receptor gene polymorphisms in suicidal behaviour among SLE patients remains unclear in the context of established clinical and psychosocial factors. We aimed to...
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