Article
Burkholderia cenocepacia integrates cis-2-dodecenoic acid and cyclic dimeric guanosine monophosphate signals to control virulence.
Proceedings of the National Academy of Sciences of the United States of America - 5 Dec 2017
Yang Chunxi, Cui Chaoyu, Ye Qiumian, Kan Jinhong, Fu Shuna, Song Shihao, Huang Yutong, He Fei, Zhang Lian-Hui, Jia Yantao, Gao Yong-Gui, Harwood Caroline S, Deng Yinyue
Abstract excerpt
Quorum sensing (QS) signals are used by bacteria to regulate biological functions in response to cell population densities. Cyclic diguanosine monophosphate (c-di-GMP) regulates cell functions in response to diverse environmental chemical and physical signals that bacteria perceive. In Burkholderia cenocepacia, the QS signal receptor RpfR degrades intracellular c-di-GMP when it senses the QS signal...
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