Article
Mutation of the cyclic di-GMP phosphodiesterase gene in Burkholderia lata SK875 attenuates virulence and enhances biofilm formation.
Journal of microbiology (Seoul, Korea) - 1 Oct 2017
Jung Hae-In, Kim Yun-Jung, Lee Yun-Jung, Lee Hee-Soo, Lee Jung-Kee, Kim Soo-Ki
Abstract excerpt
Burkholderia sp. is a gram-negative bacterium that commonly exists in the environment, and can cause diseases in plants, animals, and humans. Here, a transposon mutant library of a Burkholderia lata isolate from a pig with swine respiratory disease in Korea was screened for strains showing attenuated virulence in Caenorhabditis elegans. One such mutant was obtained, and the Tn5 insertion junction was mapped to...
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