Article
Cis-2-dodecenoic acid receptor RpfR links quorum-sensing signal perception with regulation of virulence through cyclic dimeric guanosine monophosphate turnover.
Proceedings of the National Academy of Sciences of the United States of America - 18 Sept 2012
Deng Yinyue, Schmid Nadine, Wang Chao, Wang Jianhe, Pessi Gabriella, Wu Donghui, Lee Jasmine, Aguilar Claudio, Ahrens Christian H, Chang Changqing, Song Haiwei, Eberl Leo, Zhang Lian-Hui
Abstract excerpt
Many bacterial pathogens produce diffusible signal factor (DSF)-type quorum sensing (QS) signals in modulation of virulence and biofilm formation. Previous work on Xanthomonas campestris showed that the RpfC/RpfG two-component system is involved in sensing and responding to DSF signals, but little is known in other microorganisms. Here we show that in Burkholderia cenocepacia the DSF-family signal...
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