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Contribution of parasite and host genotype to immunopathology of schistosome infections.

Parasites & vectors - 7 May 2024

Jutzeler Kathrin S, Le Clec'h Winka, Chevalier Frédéric D, Anderson Timothy J C

Abstract excerpt

BACKGROUND: The role of pathogen genotype in determining disease severity and immunopathology has been studied intensively in microbial pathogens including bacteria, fungi, protozoa and viruses but is poorly understood in parasitic helminths. The medically important blood fluke Schistosoma mansoni is an excellent model system to study the impact of helminth genetic variation on immunopathology. Our laboratory has...

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PMID: 38711063
DOI: 10.1186/s13071-024-06286-6
PMCID: PMC11073996

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