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Article

MicroRNAs as predictive biomarkers for myocardial injury in aged mice following myocardial infarction

18 Nov 2017

Abstract excerpt

The occurrence of myocardial infarction (MI) increases appreciably with age. In the Framingham Heart Study, the incidence of MI more than doubles for men and increases more than five-fold in women (ages 55-64 years compared to 85-94 years). MicroRNAs (miRNAs) quantitatively regulate their target's expression post-transcriptionally by either silencing action through binding at the 3'UTR domains or degrading the...

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PMID: 29150941
DOI: 10.1002/jcp.26283

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