Article
Obstruction phenotype as a predictor of asthma severity and instability in children.
The Journal of allergy and clinical immunology - 1 Oct 2018
Sorkness Ronald L, Zoratti Edward M, Kattan Meyer, Gergen Peter J, Evans Michael D, Visness Cynthia M, Gill Michelle, Khurana Hershey Gurjit K, Kercsmar Carolyn M, Liu Andrew H, O'Connor George T, Pongracic Jacqueline A, Pillai Dinesh, Sorkness Christine A, Togias Alkis, Wood Robert A, Busse William W
Abstract excerpt
BACKGROUND: Small-airways instability resulting in premature airway closure has been recognized as a risk for asthma severity and poor control. Although spirometry has limited sensitivity for detecting small-airways dysfunction, a focus on the air-trapping component of obstruction might identify a risk factor for asthma instability. OBJECTIVE: We sought to use spirometric measurements to identify patterns of...
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