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Article

The Neurodevelopmental Basis of Early Childhood Disruptive Behavior: Irritable and Callous Phenotypes as Exemplars.

The American journal of psychiatry - 1 Feb 2018

Wakschlag Lauren S, Perlman Susan B, Blair R James, Leibenluft Ellen, Briggs-Gowan Margaret J, Pine Daniel S

Abstract excerpt

The arrival of the Journal's 175th anniversary occurs at a time of recent advances in research, providing an ideal opportunity to present a neurodevelopmental roadmap for understanding, preventing, and treating psychiatric disorders. Such a roadmap is particularly relevant for early-childhood-onset neurodevelopmental conditions, which emerge when experience-dependent neuroplasticity is at its peak. Employing a...

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Identifiers

PMID: 29145753
DOI: 10.1176/appi.ajp.2017.17010045
PMCID: PMC6075952

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