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Clinical Application of Circulating Tumor DNA in the Genetic Analysis of Patients with Advanced GIST

13 Nov 2017

Abstract excerpt

Abstract Gastrointestinal stromal tumors (GIST) are the most common mesenchymal tumor of digestive tract. In the past, tissue biopsy was the main method for the diagnosis of GISTs. Although, circulating tumor DNA (ctDNA) detection by next-generation sequencing (NGS) may be a feasible and replaceable method for diagnosis of GISTs. We retrospectively analyzed the data for ctDNA and tissue DNA detection from 32...

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PMID: 29133619
DOI: 10.1158/1535-7163.mct-17-0436

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