Article
Mitochondrial gene polymorphism is associated with gut microbial communities in mice.
Scientific reports - 10 Nov 2017
Hirose Misa, Künstner Axel, Schilf Paul, Sünderhauf Annika, Rupp Jan, Jöhren Olaf, Schwaninger Markus, Sina Christian, Baines John F, Ibrahim Saleh M
Abstract excerpt
Gut microbial communities are key mediators of health and disease and have the capacity to drive the pathogenesis of diverse complex diseases including metabolic and chronic inflammatory diseases as well as aging. Host genetics is also a major determinant of disease phenotypes, whereby two different genomes play a role, the nuclear (nDNA)- and mitochondrial genome (mtDNA). We investigated the impact of mutations...
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