Article
Intraluminal valves: development, function and disease.
Disease models & mechanisms - 1 Nov 2017
Geng Xin, Cha Boksik, Mahamud Md Riaj, Srinivasan R Sathish
Abstract excerpt
The circulatory system consists of the heart, blood vessels and lymphatic vessels, which function in parallel to provide nutrients and remove waste from the body. Vascular function depends on valves, which regulate unidirectional fluid flow against gravitational and pressure gradients. Severe valve disorders can cause mortality and some are associated with severe morbidity. Although cardiac valve defects can be...
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