Muscadine Grape Skin Extract (MPX) in Men with Biochemically Recurrent Prostate Cancer: A Randomized, Multicenter, Placebo-Controlled Clinical Trial.

doi:10.1158/1078-0432.CCR-17-1100

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Article

Muscadine Grape Skin Extract (MPX) in Men with Biochemically Recurrent Prostate Cancer: A Randomized, Multicenter, Placebo-Controlled Clinical Trial.

Clinical cancer research : an official journal of the American Association for Cancer Research - 15 Jan 2018

Paller Channing J, Zhou Xian C, Heath Elisabeth I, Taplin Mary-Ellen, Mayer Tina, Stein Mark N, Bubley Glenn J, Pili Roberto, Hudson Tamaro, Kakarla Radhika, Abbas Muneer M, Anders Nicole M, Dowling Donna, King Serina, Bruns Ashley B, Wagner William D, Drake Charles G, Antonarakis Emmanuel S, Eisenberger Mario A, Denmeade Samuel R, Rudek Michelle A, Rosner Gary L, Carducci Michael A

Abstract excerpt

Purpose: MuscadinePlus (MPX), a commercial preparation of pulverized muscadine grape skin, was evaluated as a therapeutic option for men with biochemically recurrent (BCR) prostate cancer wishing to defer androgen deprivation therapy.Experimental Design: This was a 12-month, multicenter, placebo-controlled, two-dose, double-blinded trial of MPX in 125 men with BCR prostate cancer, powered to detect a PSA doubling...

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PMID: 29113986
DOI: 10.1158/1078-0432.CCR-17-1100
PMCID: PMC5771949

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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