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Article

B Lymphoblastic Leukemia/Lymphoma With Burkitt-like Morphology and IGH/MYC Rearrangement: Report of 3 Cases in Adult Patients.

The American journal of surgical pathology - 1 Feb 2018

Li Yiting, Gupta Gunjan, Molofsky Ari, Xie Yi, Shihabi Nader, McCormick Jane, Jaffe Elaine S

Abstract excerpt

Isolated MYC rearrangement without other recurrent genetic abnormalities is rare in B lymphoblastic leukemia/lymphoma (B-ALL/LBL), with most cases reported in pediatric patients. We report 3 adult cases with lymphoblasts showing a precursor B cell immunophenotype, and isolated MYC/IGH translocation. All 3 cases occurred in male patients with initial presentation of diffuse lymphadenopathy. Cases 1 and 2 had B-ALL...

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Topics

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Share to Burkitt Lymphoma
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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Gene Rearrangement, B-Lymphocyte, Heavy Chain

Share to Genes, Immunoglobulin Heavy Chain

Share to Immunophenotyping

Share to In Situ Hybridization, Fluorescence

Share to Precursor B-Cell Lymphoblastic Leukemia-Lymphoma

Share to Proto-Oncogene Proteins c-myc

Source

Open in PubMed Open full text

Identifiers

PMID: 29112016
DOI: 10.1097/PAS.0000000000000982
PMCID: PMC5762415

Genes

MYC
IGH
BCL6
BCL2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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