Article
Resistance mechanisms of linezolid-nonsusceptible enterococci in Korea: low rate of 23S rRNA mutations in Enterococcus faecium.
Journal of medical microbiology - 1 Dec 2017
Lee Sae-Mi, Huh Hee Jae, Song Dong Joon, Shim Hyang Jin, Park Kyung Sun, Kang Cheol-In, Ki Chang-Seok, Lee Nam Yong
Abstract excerpt
PURPOSE: To investigate linezolid-resistance mechanisms in linezolid-nonsusceptible enterococci (LNSE) isolated from a tertiary hospital in Korea. METHODOLOGY: Enterococcal isolates exhibiting linezolid MICs ≥4 mg l-1 that were isolated between December 2011 and May 2016 were investigated by PCR and sequencing for mutations in 23S rRNA or ribosomal proteins (L3, L4 and L22) and for the presence of cfr, cfr(B) and...
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