Article
Clinical predictors of conversion to bipolar disorder in a prospective longitudinal familial high-risk sample: focus on depressive features.
Psychological medicine - 1 Jul 2018
Frankland Andrew, Roberts Gloria, Holmes-Preston Ellen, Perich Tania, Levy Florence, Lenroot Rhoshel, Hadzi-Pavlovic Dusan, Breakspear Michael, Mitchell Philip B
Abstract excerpt
BACKGROUND: Identifying clinical features that predict conversion to bipolar disorder (BD) in those at high familial risk (HR) would assist in identifying a more focused population for early intervention. METHOD: In total 287 participants aged 12-30 (163 HR with a first-degree relative with BD and 124 controls (CONs)) were followed annually for a median of 5 years. We used the baseline presence of DSM-IV...
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