Article
Heritable Variation, With Little or No Maternal Effect, Accounts for Recurrence Risk to Autism Spectrum Disorder in Sweden.
Biological psychiatry - 1 Apr 2018
Yip Benjamin Hon Kei, Bai Dan, Mahjani Behrang, Klei Lambertus, Pawitan Yudi, Hultman Christina M, Grice Dorothy E, Roeder Kathryn, Buxbaum Joseph D, Devlin Bernie, Reichenberg Abraham, Sandin Sven
Abstract excerpt
BACKGROUND: Autism spectrum disorder (ASD) has both genetic and environmental origins, including potentially maternal effects. Maternal effects describe the association of one or more maternal phenotypes with liability to ASD in progeny that are independent of maternally transmitted risk alleles. While maternal effects could play an important role, consistent with association to maternal traits such as immune...
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