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Article

Gene expression and risk of leukemic transformation in myelodysplasia

2 Nov 2017

Abstract excerpt

= .02). Leukemic transformation was limited to the IMP subgroup. The prognostic significance of our classification was validated in an independent cohort of 183 patients. We also constructed a model to predict the subgroups using gene expression profiles of unfractionated bone marrow mononuclear cells (BMMNCs). The model successfully predicted clinical outcomes in a test set of 114 patients with BMMNC samples....

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PMID: 29097382
DOI: 10.1182/blood-2017-05-783050

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