A proposed role for diffusible signal factors in the biofilm formation and morphological transformation of Helicobacter pylori

Abstract excerpt

Due to the increasing resistance of Helicobacter pylori to antibiotics, there is a growing need for new strategies for the effective eradication of this pathogen. The inhibition of quorum-sensing activity in most microorganisms leads to a decrease in virulence. A different reaction is observed in H. pylori, as interfering with the production of autoinducer-2 initiates biofilm formation and increases the survival...

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