Article
Impaired Specific Antifungal Immunity in CARD9-Deficient Patients with Phaeohyphomycosis.
The Journal of investigative dermatology - 1 Mar 2018
Wang Xiaowen, Zhang Ruijun, Wu Weiwei, Song Yinggai, Wan Zhe, Han Wenling, Li Ruoyu
Abstract excerpt
Phaeohyphomycosis is a group of severe infections caused by dematiaceous fungi. We previously identified CARD9 deficiencies in four Chinese patients with phaeohyphomycosis caused by Phialophora verrucosa. In this study, we sought to identify the genetic and immunological mechanisms underlying rare dematiaceous fungal infections in three otherwise healthy patients with phaeohyphomycosis caused by Exophiala...
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