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Article

Detection and assessment of copy number variation using PacBio long-read and Illumina sequencing in New Zealand dairy cattle.

Journal of dairy science - 1 Jul 2017

Couldrey C, Keehan M, Johnson T, Tiplady K, Winkelman A, Littlejohn M D, Scott A, Kemper K E, Hayes B, Davis S R, Spelman R J

Abstract excerpt

Single nucleotide polymorphisms have been the DNA variant of choice for genomic prediction, largely because of the ease of single nucleotide polymorphism genotype collection. In contrast, structural variants (SV), which include copy number variants (CNV), translocations, insertions, and inversions, have eluded easy detection and characterization, particularly in nonhuman species. However, evidence increasingly...

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PMID: 28456410
DOI: 10.3168/jds.2016-12199

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