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Generation of two induced pluripotent stem cell (iPSC) lines from X-linked adrenoleukodystrophy (X-ALD) patients with adrenomyeloneuropathy (AMN).

Stem cell research - 1 Dec 2017

Son Daryeon, Quan Zhejiu, Kang Phil Jun, Park Gyuman, Kang Hoon-Chul, You Seungkwon

Abstract excerpt

X-linked adrenoleukodystrophy (X-ALD) is an inherited disorder caused by a mutation in the ATP-binding cassette transporter subfamily D member 1 (ABCD1) gene. We generated two induced pluripotent stem cell (iPSC) lines from X-ALD patients with adrenomyeloneuropathy (AMN) by Sendai virus containing OCT4, SOX2, KLF4 and c-MYC. Established iPSC lines expressed various pluripotency markers, had differentiation...

Topics

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Adrenoleukodystrophy
ATP Binding Cassette Transporter, Subfamily D, Member 1
Cells, Cultured
Flow Cytometry
Immunohistochemistry

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Induced Pluripotent Stem Cells

Kruppel-Like Factor 4

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Identifiers

PMID: 29065337
DOI: 10.1016/j.scr.2017.10.003

Genes

ABCD1
AMN
KLF4
MYC
SOX2

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026.

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