Article
Influence of Apolipoprotein E polymorphism on susceptibility of Wilson disease.
Annals of human genetics - 1 Mar 2018
Roy Shubhrajit, Ganguly Kausik, Pal Prosenjit, Ghosh Sampurna, Das Shyamal K, Gangopadhyay Prasanta K, Bavdekar Ashish, Ray Kunal, Sengupta Mainak, Ray Jharna
Abstract excerpt
Wilson disease (WD) is an autosomal-recessive disorder caused by mutations in the ATP7B gene leading to abnormal copper deposition in liver and brain. WD manifests diverse neurological and hepatic phenotypes and different age of onset, even among the siblings, with same mutational background suggesting complex nature of the disease and involvement of other candidate genes. In that context, Apolipoprotein E (APOE)...
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