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Article

Apolipoprotein E gene (APOE) genotype in Wilson's disease: impact on clinical presentation.

Parkinsonism & related disorders - 1 May 2012

Litwin T, Gromadzka G, Członkowska A

Abstract excerpt

BACKGROUND: Wilson's disease (WD), an inherited copper metabolism disorder that leads to pathological tissue copper accumulation and secondary organ damage, is caused by mutations in the ATP-ase 7B gene (ATP7B). The apolipoprotein E gene (APOE) alleles ε2, ε3, and ε4 produce three different apoE isoforms with different biological effects, which can determine risks of many human diseases, including...

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Identifiers

PMID: 22221592
DOI: 10.1016/j.parkreldis.2011.12.005

Genes

APOE

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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