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Article

Generation and characterization of a human iPSC line SANi005-A containing the gray platelet associated heterozygous mutation p.Q287* in GFI1B.

Stem cell research - 1 Dec 2017

Hansen Marten, Varga Eszter, Wüst Tatjana, Mellink Clemens, van der Kevie-Kersemaekers Anne-Marie, Marneth Anne E, von Lindern Marieke, van der Reijden Bert, van den Akker Emile

Abstract excerpt

Peripheral blood mononuclear cells were isolated from an individual harboring a heterozygous c.859C→T p.Q287* mutation in GFI1B, causing an autosomal dominant bleeding disorder, platelet type, 17 (BDPLT17). PBMCs were differentiated to erythroblasts and reprogrammed by lentiviral delivery of a self-silencing hOKSM polycistronic vector. Pluripotency of iPSC line was confirmed by expression of associated markers...

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Identifiers

PMID: 29055225
DOI: 10.1016/j.scr.2017.10.008

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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