Article
The interactions among organophosphate pesticide exposure, oxidative stress, and genetic polymorphisms of dopamine receptor D4 increase the risk of attention deficit/hyperactivity disorder in children.
Environmental research - 1 Jan 2018
Chang Chia-Huang, Yu Ching-Jung, Du Jung-Chieh, Chiou Hsien-Chih, Chen Hsin-Chang, Yang Winnie, Chung Ming-Yi, Chen Ying-Sheue, Hwang Betau, Mao I-Fang, Chen Mei-Lien
Abstract excerpt
OBJECTIVE: The aim of this study was to clarify the association between organophosphate pesticides (OPs) and attention-deficit/hyperactivity disorder (ADHD) related to oxidative stress and genetic polymorphisms. METHODS: This case-control study enrolled 93 children with ADHD and 112 control children in north Taiwan. Six dialkyl phosphate (DAP) metabolites of OPs and oxidative stress biomarkers were analyzed....
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