Article
The association of LMP7 and TAP2 gene polymorphisms with treatment response to interferon/ribavirin in patients with genotype 1 chronic hepatitis C.
International journal of molecular medicine - 1 Dec 2017
Zang Feng, Yao Yinan, Liu Mei, Fan Haozhi, Yue Ming, Chen Mingzhu, Wang Jie, Yu Rongbin, Huang Peng
Abstract excerpt
Previous studies have highlighted the important role of genes related to antigen presentation in the spontaneous clearance of hepatitis C virus. The present study aimed to explore the association between TAP, LMP and tapasin gene polymorphism and treatment response in chronic hepatitis C virus (CHC) patients. Six single nucleotide polymorphisms in TAP, LMP and tapasin genes were genotyped among 352 Chinese...
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