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Article

Rare and common variants of APOB and PCSK9 in Korean patients with extremely low low-density lipoprotein-cholesterol levels.

PloS one - 1 Jan 2017

Lee Chan Joo, Lee Yunbeom, Park Sungha, Kang Seok-Min, Jang Yangsoo, Lee Ji Hyun, Lee Sang-Hak

Abstract excerpt

BACKGROUND: Screening of variants, related to lipid metabolism in patients with extreme cholesterol levels, is a tool used to identify targets affecting cardiovascular outcomes. The aim of this study was to examine the prevalence and characteristics of rare and common variants of APOB and PCSK9 in Korean patients with extremely low low-density lipoprotein-cholesterol (LDL-C) levels. METHODS: Among 13,545...

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Topics

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Share to Apolipoprotein B-100
Share to Cholesterol, LDL

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Cohort Studies

Share to Genetic Variation

Share to Hypobetalipoproteinemias

Share to Polymorphism, Single Nucleotide

Share to Proprotein Convertase 9

Share to Republic of Korea

Source

Open in PubMed Open full text

Identifiers

PMID: 29036232
DOI: 10.1371/journal.pone.0186446
PMCID: PMC5643101

Genes

APOB
PCSK9

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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