Article
Interleukin 1β polymorphism and serum level are associated with pediatric asthma.
Pediatric pulmonology - 1 Dec 2017
Sobkowiak Paulina, Wojsyk-Banaszak Irena, Kowalewska Maja, Wasilewska Eliza, Langwiński Wojciech, Kycler Zdzisława, Skibińska Maria, Bręborowicz Anna, Jassem Ewa, Szczepankiewicz Aleksandra
Abstract excerpt
BACKGROUND AND AIM: Interleukin-1 is a pro-inflammatory cytokine found in two forms (α and β). The α form is mainly cell-bound, whereas IL-1β is primarily secreted by macrophages in response to immune system stimulation. We hypothesized that polymorphic variants of interleukin 1 genes may play a role in childhood asthma risk. The aim of this study was to investigate if IL-1α and β polymorphism is associated with...
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