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Mutational spectrum in breast cancer associated BRCA1 and BRCA2 genes in Colombia.

Colombia medica (Cali, Colombia) - 30 Jun 2017

Briceño-Balcázar Ignacio, Gómez-Gutiérrez Alberto, Díaz-Dussán Natalia Andrea, Noguera-Santamaría María Claudia, Díaz-Rincón Diego, Casas-Gómez María Consuelo

Abstract excerpt

INTRODUCTION: The risk of developing breast and ovarian cancer is higher in families that carry mutations in BRCA1 or BRCA2 genes, and timely mutation detection is critical. OBJECTIVE: To identify the presence of mutations in the Colombian population and evaluate two testing strategies. METHODS: From a total universe of 853 individual blood samples referred for BRCA1 and BRCA2 typing, 256 cases were analyzed by...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 29021639
PMCID: PMC5625557

Genes

BRCA1
BRCA2

Provenance

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