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Article

Maternal obesity heritably perturbs offspring metabolism for three generations without serial programming.

International journal of obesity (2005) - 1 Apr 2018

Eaton S A, Aiken A J, Young P E, Ho J W K, Cropley J E, Suter C M

Abstract excerpt

Maternal obesity can program offspring metabolism across multiple generations. It is not known whether multigenerational effects reflect true inheritance of the induced phenotype, or are due to serial propagation of the phenotype through repeated exposure to a compromised gestational milieu. Here we sought to distinguish these possibilities, using the Avy mouse model of maternal obesity. In this model, F1 sons of...

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Identifiers

PMID: 28984844
DOI: 10.1038/ijo.2017.247

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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