Article
Contributors to the substantial variation in on-treatment testosterone levels in men receiving transdermal testosterone gels in randomized trials.
Andrology - 1 Jan 2018
Bhasin S, Travison T G, O'Brien L, MacKrell J, Krishnan V, Ouyang H, Pencina K, Basaria S
Abstract excerpt
There is substantial inter-individual variability in serum testosterone levels in hypogonadal men treated with testosterone gels. We aimed to elucidate participant-level factors that contribute to inter-individual variability in testosterone levels during testosterone therapy. An exploratory aim was to determine whether polymorphisms in genes encoding testosterone-metabolizing enzymes could explain the variation...
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