Article
Large Variation in the Ratio of Mitochondrial to Nuclear Mutation Rate across Animals: Implications for Genetic Diversity and the Use of Mitochondrial DNA as a Molecular Marker.
Molecular biology and evolution - 1 Nov 2017
Allio Remi, Donega Stefano, Galtier Nicolas, Nabholz Benoit
Abstract excerpt
It is commonly assumed that mitochondrial DNA (mtDNA) evolves at a faster rate than nuclear DNA (nuDNA) in animals. This has contributed to the popularity of mtDNA as a molecular marker in evolutionary studies. Analyzing 121 multilocus data sets and four phylogenomic data sets encompassing 4,676 species of animals, we demonstrate that the ratio of mitochondrial over nuclear mutation rate is highly variable among...
Topics
- Animals
- Biological Evolution
- Biomarkers
- Cell Nucleus
- DNA, Mitochondrial
- Databases, Nucleic Acid
- Evolution, Molecular
- Genetic Speciation
- Genetic Variation
- Genetics, Population
- Genome
- Mitochondria
- Mutation
- Mutation Rate