Article
Acute leukemia in adolescents and young adults.
[Rinsho ketsueki] The Japanese journal of clinical hematology - 1 Jan 2000
Tomizawa Daisuke
Abstract excerpt
Both acute lymphoblastic leukemia (ALL) and acute myeloid leukemia (AML) are common malignant diseases in adolescents and young adults (AYAs). Recent advances in genomic studies have helped us understand the biological nature of acute leukemia in AYAs; higher frequency of Ph-like ALL and rearrangements in DUX4, ERG, MEF2D, and ZNF384 genes in AYAs with ALL and higher frequency of FLT3-ITD, NPM1, IDH1/2, DNMT3A,...
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