Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Context-specific effects of genetic variants associated with autoimmune disease.

Human molecular genetics - 1 Oct 2017

Jonkers Iris H, Wijmenga Cisca

Abstract excerpt

Autoimmune diseases such as rheumatoid arthritis and coeliac disease are typical examples of complex genetic diseases caused by a combination of genetic and non-genetic risk factors. Insight into the genetic risk factors (single nucleotide polymorphisms (SNPs)) has increased since genome-wide association studies (GWAS) became possible in 2007 and, for individual diseases, SNPs can now explain some 15-50% of...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Arthritis, Rheumatoid
Share to Autoimmune Diseases
Share to Autoimmunity

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Gene Expression Regulation

Share to Gene Regulatory Networks

Share to Genome-Wide Association Study

Share to Quantitative Trait Loci

Share to Risk Factors

Source

Open in PubMed Open full text

Identifiers

PMID: 28977443
DOI: 10.1093/hmg/ddx254
PMCID: PMC5886469

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Context-specific effects of genetic variants associated with autoimmune disease.PMID 28977443Read ↗

Autoimmune diseases: insights from genome-wide association studies.Semantic proximity Read ↗

Common genetic factors among autoimmune diseases.Semantic proximity Read ↗

Human genetics offers an emerging picture of common pathways and mechanisms in autoimmunity.Semantic proximity Read ↗

Shared genetics in coeliac disease and other immune-mediated diseases.Semantic proximity Read ↗

Emerging patterns of genetic overlap across autoimmune disordersSemantic proximity Read ↗

Recent advances in the genetics of autoimmune disease.Semantic proximity Read ↗

Rare variants and autoimmune disease.Semantic proximity Read ↗

Autoimmune diseases - connecting risk alleles with molecular traits of the immune system.Semantic proximity Read ↗

Gene-environment interaction in autoimmune disease.Semantic proximity Read ↗

Rare genetic variants in systemic autoimmunity.Semantic proximity Read ↗

Beyond disease susceptibility-Leveraging genome-wide association studies for new insights into complex disease biology.Semantic proximity Read ↗

Clinical implications of shared genetics and pathogenesis in autoimmune diseases.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.