Article
Prediction of evolutionary constraint by genomic annotations improves functional prioritization of genomic variants in maize.
Genome biology - 1 Sept 2022
Ramstein Guillaume P, Buckler Edward S
Abstract excerpt
BACKGROUND: Crop improvement through cross-population genomic prediction and genome editing requires identification of causal variants at high resolution, within fewer than hundreds of base pairs. Most genetic mapping studies have generally lacked such resolution. In contrast, evolutionary approaches can detect genetic effects at high resolution, but they are limited by shifting selection, missing data, and low...
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