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Article

Next-Generation Sequencing in the Clinical Setting Clarifies Patient Characteristics and Potential Actionability.

Cancer research - 15 Nov 2017

Bieg-Bourne Cheyennedra C, Millis Sherri Z, Piccioni David E, Fanta Paul T, Goldberg Michael E, Chmielecki Juliann, Parker Barbara A, Kurzrock Razelle

Abstract excerpt

Enhancements in clinical-grade next-generation sequencing (NGS) have fueled the advancement of precision medicine in the clinical oncology field. Here, we survey the molecular profiles of 1,113 patients with diverse malignancies who successfully underwent clinical-grade NGS (236-404 genes) in an academic tertiary cancer center. Among the individual tumors examined, the majority showed at least one detectable...

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Identifiers

PMID: 28939679
DOI: 10.1158/0008-5472.CAN-17-1569
PMCID: PMC5690871

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KRAS
TERT

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