Article
Genetic Discoveries Drive Molecular Analyses and Targeted Therapeutic Options in the Epilepsies.
Current neurology and neuroscience reports - 1 Oct 2015
Dhindsa Ryan S, Goldstein David B
Abstract excerpt
Epilepsy is a serious neurological disease with substantial genetic contribution. We have recently made major advances in understanding the genetics and etiology of the epilepsies. However, current antiepileptic drugs are ineffective in nearly one third of patients. Most of these drugs were developed without knowledge of the underlying causes of the epilepsy to be treated; thus, it seems reasonable to assume that...
Topics
- Animals
- Anticonvulsants
- Electrodes, Implanted
- Epilepsy
- Genetic Predisposition to Disease
- Humans
- Mutation