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Article

Apposition to endometrial epithelial cells activates mouse blastocysts for implantation

25 Jul 2017

Abstract excerpt

STUDY QUESTION: How do interactions between blastocyst-stage embryos and endometrial epithelial cells regulate the early stages of implantation in an in vitro model? SUMMARY ANSWER: Mouse blastocyst apposition with human endometrial epithelial cells initiates trophectoderm differentiation to trophoblast, which goes on to breach the endometrial epithelium. WHAT IS KNOWN ALREADY: In vitro models using mouse...

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Identifiers

PMID: 28911212
DOI: 10.1093/molehr/gax043

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