Article
Therapy-related Acute Leukemia With Mixed Phenotype and Novel t(1: 6)(q25;p23) After Treatment for High-risk Neuroblastoma.
Journal of pediatric hematology/oncology - 1 Nov 2017
Whittle Sarah B, Punia Jyotinder N, López-Terrada Dolores, Gaikwad Amos, Hampton Oliver A, Heczey Andras
Abstract excerpt
Neuroblastoma is the most common extracranial malignancy of childhood. Patients with high-risk disease receive multimodal treatment including chemotherapy combinations containing alkylating agents and topoisomerase inhibitors with potential for inducing therapy-related malignancy later in life. Most commonly, cytogenetic changes of pediatric therapy-related myelodysplastic syndrome/acute myeloid leukemia involve...
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