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Role of Microbiota in Strengthening Ocular Mucosal Barrier Function Through Secretory IgA

11 Sept 2017

Abstract excerpt

Purpose: The purpose of this study was to evaluate mechanisms controlling secretory IgA (SIgA) production, thereby ensuring maintenance of ocular surface health. Methods: To determine whether the presence of specific gut commensal species regulates SIgA levels and IgA transcripts in the eye-associated lymphoid tissues (EALT), specific-pathogen-free (SPF) Swiss Webster (SW) mice were treated with antibiotic...

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PMID: 28892827
DOI: 10.1167/iovs.17-22119

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