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Article

Serum lipid alterations in GBA-associated Parkinson's disease.

Parkinsonism & related disorders - 1 Nov 2017

Guedes Leonor Correia, Chan Robin Barry, Gomes Marcos António, Conceição Vasco A, Machado Raquel Bouça, Soares Tiago, Xu Yimeng, Gaspar Paulo, Carriço Joao André, Alcalay Roy N, Ferreira Joaquim J, Outeiro Tiago Fleming, Miltenberger-Miltenyi Gabriel

Abstract excerpt

INTRODUCTION: Mutations in the GBA gene, encoding for the lysosomal enzyme glucocerebrosidase, are associated with Gaucher disease. Alterations in plasma sphingolipids have been reported in Gaucher, and similarly in brain extracts in Lewy body disease. As GBA mutations are prevalent risk factors for Parkinson's disease and overlap of molecular pathways are presumable, here we assessed the lipid profiles in...

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Identifiers

PMID: 28890071
DOI: 10.1016/j.parkreldis.2017.08.026

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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