Article
Phenotype in combination with genotype improves outcome prediction in acute myeloid leukemia: a report from Children's Oncology Group protocol AAML0531.
Haematologica - 1 Dec 2017
Voigt Andrew P, Brodersen Lisa Eidenschink, Alonzo Todd A, Gerbing Robert B, Menssen Andrew J, Wilson Elisabeth R, Kahwash Samir, Raimondi Susana C, Hirsch Betsy A, Gamis Alan S, Meshinchi Soheil, Wells Denise A, Loken Michael R
Abstract excerpt
Diagnostic biomarkers can be used to determine relapse risk in acute myeloid leukemia, and certain genetic aberrancies have prognostic relevance. A diagnostic immunophenotypic expression profile, which quantifies the amounts of distinct gene products, not just their presence or absence, was established in order to improve outcome prediction for patients with acute myeloid leukemia. The immunophenotypic expression...
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