Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Genetic Mechanisms Contribute to the Development of Heart Failure in Patients with Atrioventricular Block and Right Ventricular Apical Pacing.

Scientific reports - 6 Sept 2017

Liu Nana, Zheng Min, Li Shijie, Bai Hui, Liu Zhouying, Hou Cui Hong, Zhang Shu, Pu Jielin

Abstract excerpt

Right ventricular apical (RVA) pacing can lead to progressive left ventricular dysfunction and heart failure (HF), even in patients with normal cardiac structure and function. Our study conducted candidate gene screening and lentivirus transfected neonatal rat cardiomyocytes (NRCMs) to explore the genetic and pathogenic mechanisms of RVA pacing induced cardiomyopathy in third degree atrioventricular block (III...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Apoptosis
Share to Atrioventricular Block

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Cardiac Pacing, Artificial

Share to Comorbidity

Share to Follow-Up Studies

Share to Heart Failure

Share to Heart Function Tests

Share to Lamin Type A

Source

Open in PubMed Open full text

Identifiers

PMID: 28878402
DOI: 10.1038/s41598-017-11211-2
PMCID: PMC5587648

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 8 closest

Genetic Mechanisms Contribute to the Development of Heart Failure in Patients with Atrioventricular Block and Right Ventricular Apical Pacing.PMID 28878402Read ↗

Intracellular calcium current disorder and disease phenotype in OBSCN mutant iPSC-based cardiomyocytes in arrhythmogenic right ventricular cardiomyopathySemantic proximity Read ↗

Dysfunction of Myosin Light-Chain 4 (MYL4) Leads to Heritable Atrial Cardiomyopathy With Electrical, Contractile, and Structural Components: Evidence From Genetically-Engineered Rats.Semantic proximity Read ↗

Arrhythmogenic right ventricular cardiomyopathy: From genetics to diagnostic and therapeutic challengesSemantic proximity Read ↗

Induced pluripotent stem cells in the inherited cardiomyopathies: From disease mechanisms to novel therapies.Semantic proximity Read ↗

Genetics of hypertrophic and dilated cardiomyopathy.Semantic proximity Read ↗

Targeted Therapies in Genetic Dilated and Hypertrophic Cardiomyopathies: From Molecular Mechanisms to Therapeutic Targets. A Position Paper from the Heart Failure Association (HFA) and the Working Group on Myocardial Function of the European Society of Cardiology (ESC)Semantic proximity Read ↗

Molecular Genetics and Pathogenesis of Arrhythmogenic Right Ventricular Cardiomyopathy: A Disease of Cardiac Stem CellsSemantic proximity Read ↗

Clinical and Mechanistic Insights Into the Genetics of Cardiomyopathy.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.