Article
Culture-independent metagenomics supports discovery of uncultivable bacteria within the genus Chlamydia.
Scientific reports - 6 Sept 2017
Taylor-Brown Alyce, Spang Labolina, Borel Nicole, Polkinghorne Adam
Abstract excerpt
Advances in culture-independent methods have meant that we can more readily detect and diagnose emerging infectious disease threats in humans and animals. Metagenomics is fast becoming a popular tool for detection and characterisation of novel bacterial pathogens in their environment, and is particularly useful for obligate intracellular bacteria such as Chlamydiae that require labour-intensive culturing. We have...
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