Comparative quantitative proteomic analysis of disease stratified laser captured microdissected human islets identifies proteins and pathways potentially related to type 1 diabetes

Abstract excerpt

Type 1 diabetes (T1D) is a chronic inflammatory disease that is characterized by autoimmune destruction of insulin-producing pancreatic beta cells. The goal of this study was to identify novel protein signatures that distinguish Islets from patients with T1D, patients who are autoantibody positive without symptoms of diabetes, and from individuals with no evidence of disease. High resolution high mass accuracy...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to Advanced Proteomics Techniques and Applications
• Share to Diabetes and associated disorders
• Share to Pancreatic function and diabetes