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Article

The Association Between HSP90/topoisomerase I Immunophenotype and the Clinical Features of Colorectal Cancers in Respect to KRAS Gene Status.

Anticancer research - 1 Sept 2017

Bar Julia K, Lis-Nawara Anna, Grelewski Piotr, Noga Leszek, Grzebieniak Zygmunt, Jeleń Michał

Abstract excerpt

AIM: The aim of this study was to investigate heat shock protein 90 (HSP90) and topoisomerase I (Topo I) expression and the association between both proteins and clinicopathological parameters of colorectal cancer (CRC), in order to describe their role in tumor biology regarding to Kirsten Ras (KRAS) - positive/negative cases. MATERIALS AND METHODS: Expression of HSP90 and Topo I, and KRAS gene mutations were...

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Identifiers

PMID: 28870917
DOI: 10.21873/anticanres.11905

Genes

KRAS

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