Article
Independent and additive interaction between polymorphisms of tumor necrosis factor α-308 and lymphotoxin α+252 on risk of hepatocellular carcinoma related to hepatitis B.
The Kaohsiung journal of medical sciences - 1 Sept 2017
Tsai Jung-Fa, Chen Shinn-Chern, Lin Zu-Yau, Dai Chia-Yen, Huang Jee-Fu, Yu Min-Lung, Chuang Wan-Long
Abstract excerpt
This case-control study was aimed to assess the effect of genetic variants of tumor necrosis factor (TNF) α-308 and lymphotoxin (LT) α+252 on development of hepatitis B virus (HBV)-related hepatocellular carcinoma (HCC). Their gene-gene interaction was also investigated. We enrolled 200 pairs of age- and sex-matched patients with cirrhotic HBV-HCC and unrelated patients with HBV-cirrhosis alone. Polymorphisms of...
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