Article
Genome-wide association study for mandibular prognathism using microsatellite and pooled DNA method.
American journal of orthodontics and dentofacial orthopedics : official publication of the American Association of Orthodontists, its constituent societies, and the American Board of Orthodontics - 1 Sept 2017
Saito Fumio, Kajii Takashi S, Oka Akira, Ikuno Keiichiro, Iida Junichiro
Abstract excerpt
INTRODUCTION: The purpose of this study was to extend an association study from chromosome 1 to the whole genome (genome-wide association study) to find susceptibility loci of mandibular prognathism. METHODS: Two hundred forty patients diagnosed with mandibular prognathism and 360 healthy controls of Japanese descent were recruited. The typing of microsatellites covering the whole genome was conducted using a...
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